Obesity and Metabolic Unhealthiness Have Different Effects on Colorectal Neoplasms
نویسندگان
چکیده
منابع مشابه
Metabolic syndrome and different obesity phenotypes in the elderly women population: Iran’s Health System on aging
Background: Current literature has been focused on types of obesity with normal BMI (body mass index), but metabolically unhealthy.This study evaluates the prevalence of metabolical phenotypes of obesity. We also identified the best obesity index in predicting the components of metabolic syndrome (MetS). Methods: A cross-sectional study has been conducted on 164 women over 60 years. Anthropome...
متن کاملDistinct Molecular Features of Different Macroscopic Subtypes of Colorectal Neoplasms
BACKGROUND Colorectal adenoma develops into cancer with the accumulation of genetic and epigenetic changes. We studied the underlying molecular and clinicopathological features to better understand the heterogeneity of colorectal neoplasms (CRNs). METHODS We evaluated both genetic (mutations of KRAS, BRAF, TP53, and PIK3CA, and microsatellite instability [MSI]) and epigenetic (methylation sta...
متن کاملCOMPARISON OF THE EFFECTS OF INTERVAL TRAINING WITH DIFFERENT DIET ON IL-6, TNF-Α AND SOME OF METABOLIC INDEXES IN OBESITY TYPE 2 DIABETIC MEN
Background: Interleukin-6(IL-6) and Tumor Necroes Factor-alpha (TNF-α) are secreted by adipose tissue and are potential regulators of low grade inflammation and metabolic disorders in Obesity Type 2 Diabetes (OT2D). hence, present study examined the effects of interval training with different diet on low grade inflammation and some of metabolic indexes in OT2D. Methods: forty-five OT2D men were ...
متن کاملPreventive effects of Bofutsushosan on obesity and various metabolic disorders.
Visceral fat accumulation has been reported as the most important risk factor for the development of various metabolic disorders. In this study, the preventive effects of Bofutsushosan, a Japanese Kampo preparation, on obesity and various metabolic disorders were investigated focusing on visceral fat accumulation using Tsumura, Suzuki, Obese, Diabetes (TSOD) mice, which showed significant accum...
متن کاملGenetic Manipulations of PPARs: Effects on Obesity and Metabolic Disease
The interest in genetic manipulations of PPARs is as old as their discovery as receptors of ligands with beneficial clinical activities. Considering the effects of PPAR ligands on critical aspects of systemic physiology, including obesity, lipid metabolism, insulin resistance, and diabetes, gene knockout (KO) in mice is the ideal platform for both hypothesis testing and discovery of new PPAR fu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2017
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2017-00152